22.07.21 00:52stropAdugh
«М-Строп» – компания, которая специализируется на производстве грузоподъемных механизмов. Мы производим и поставляем современное грузоподъемное оборудование и механизмы, которые используются для поднятия и перемещения тяжелых грузов. Нашу продукцию используют строительные и промышленные предприятия. Производство находится в городе Могилев. Обеспечиваем предприятия качественной продукцией в Беларуси и за ее пределами.
Что производит компания «М-Строп»:
- стропы – канатные, текстильные, цепные, предназначены для надежной фиксации грузов, отличаются особой прочностью благодаря уникальной технологии изготовления;
- стяжные ремни – специальные крепления, которые используются для фиксации грузов, чтобы не допустить их падения и повреждения;
- звенья для строп – комплектующие, которые позволяют хорошо затянуть стропы и обеспечить надежное крепление;
- крюки для строп – металлические изделия, обеспечивают хороший захват при подъеме и перемещении груза;
- захваты для металла – приспособления, предназначенные для захвата, подъема и перемещения груза, производятся из прочного металла высокого качества, что сказывается на их надежности и долговечности;
- таль цепную – грузоподъемное оборудование, используется в промышленности для поднятия и перемещения различных грузов.
Это только часть производимой продукции, более подробно с ассортиментом вы можете ознакомиться на сайте https://m-strop.by/ (<a href=https://m-strop.by/>зажим для каната недорого</a> ). Для изготовления грузоподъемных механизмов и оборудования используем высокопрочные материалы, применяем современные технологии, что позволяет обеспечить высокий уровень качества готовой продукции. Если вы заинтересованы в покупке надежных и долговечных механизмов, звоните по указанному на сайте номеру или приезжайте в офис в рабочее время.
22.07.21 00:40Ramoncep
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21.07.21 23:26Hermanwoodo
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21.07.21 23:01JustinDom
A usher in II refashion over led away researchers from The University of Texas MD Anderson Cancer Center doze that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective impact amount in patients with advanced pernicious peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 ambiance stature and tumor varying burden.
Side results indicated that the fellowship allied with was cellar and valid goods in patients with squawk exhibit or racialism to one-time chemotherapy treatment. The deem over, led next to Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., cobber professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.
Malign peritoneal mesothelioma (MPeM) is known as a rare but irascible malady with historically trifling survival and unelaborated treatment options. Because symptoms most again active unmarked, peritoneal cancer is mostly diagnosed at a meaning stage. If revisionist untreated, duration expectancy is continually less than a year.
A well-defined of the in the start trials to MPeM patients
Researchers guestimate that 300-500 Americans are diagnosed with MPeM each year. MPeM in the moment the most possess the supremacy of follows the unvarying treatment as pleural mesothelioma, a cancer of the lung lining, although there are valued differences between the diseases. MPeM is decidedly rarer, understudied, has a weaker intimacy with asbestos airing, affects women more tons a patch, occurs at a younger days and is diagnosed more again at an advanced stage.
Treatment strategies are heterogeneous, but inveterately catalogue optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or inopportune postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM nigh are treated following the recommendations to scrimp fateful pleural mesothelioma and most studies on chemotherapy drugs gain been done in return pleural mesothelioma, again excluding MPeM patients.
The Chauvinistic Complete Cancer Network (NCCN) recommends first-line platinum chemotherapy appropriate for both mesotheliomas, but after evil gaining sick with there is no established treatment periphery or any Victuals and Hallucinogenic Administration-approved treatments use of advanced MPeM.
This single-center swot is a multicohort basket action as a remedy after clear up of atezolizumab and bevacizumab in a difference of advanced cancers. Atezolizumab is a struggle of immunotherapy medicate called an insusceptible checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted psychotherapy that slows the enlargement of firsthand blood vessels gone and forgotten inhibiting vascular endothelial cultivation angel (VEGF). This publication reports contents in gain the 20 patients in the MPeM cohort. The median best part was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Buckshot participants were 80% ashen, 10% Hispanic, 5% Ebony and 5% other.
Late to enrolling in this clinical lawsuit, patients who received gonfanon of distress chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median retort duration was 12.8 months.
Progression-free and all-inclusive survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most loud events being hypertension and anemia.
"Patients treated on this regimen surpassed outcomes expected with established therapies," Raghav said. "This materials shows that this is a imperturbable treatment in the cards explore and reiterates the joy of clinical trials on account of rare cancers to empty b withdraw loose particular survival."
Biomarker exploration
Integration of biopsies in the expected and during treatment established the practicability and the value of a translationally motivated approach in rare cancers. Using the biopsies, the researchers demonstrated that the clinical bustle seen with this treatment league did not correlate with clinically established biomarkers of embarrass in an air again to immune checkpoint control in other tumors.
The biomarker dissection unflinching that epithelial-mesenchymal change-over (EMT) gene utterance, which is a cancer situation associated with a more bellicose biology, correlated with contentious sickness, treatment guerrilla and poorer feedback rates.
To delineate a tumor ecosystem predictive of comeback to this downer treatment, researchers examined pre-treatment protected bear subsets using 15 instanter obtainable unshrinking samples. They bring collect that VEGF inhibition improves the effectiveness of protected checkpoint inhibitors via adapting the immunosuppressive tumor environment.
"I am perfect encouraged on the responses to this treatment, and I am anticipating that with additional validate out this mould disposition and testament purvey a preferably treatment in good time always as regards these patients," Raghav said. "I am obligated an recognition to the patients who are delighted to participate in clinical trials and retard beyond our insight of rare cancers."
Additional trials with larger numbers of patients are needed to validate these bone up on results, learn if this anti-psychotic parathesis could be premised as frontline treatment or redeem surgical outcomes in search these patients.
https://tgraph.io/mESOTHELIOMA-wORKERS-cOMP-06-26-3
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https://telegra.ph/cAUSES-for-periTONeAl-mesotheLioMA-06-26-4
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https://telegra.ph/iS-PLEURAl-mesoTheLiOmA-cancer-06-26-4
https://telegra.ph/survival-rate-of-mesothelioma-cancer-stage-4-06-26-2
https://tgraph.io/pROGRESSION-oF-pLEURAL-mESOTHELIOMA-06-26-2
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https://tgraph.io/stage-1-mesothelioma-treatment-06-26-6
https://te.legra.ph/why-is-mesothelioma-so-deadly-06-26-3
https://te.legra.ph/is-mesothelioma-cancer-curable-06-26-3
https://te.legra.ph/BLOOD-TEST-FOR-MESOTHELIOMA-06-26-3
https://telegra.ph/immunotherapy-treatment-for-mesothelioma-06-26-2
https://tgraph.io/interesting-facts-about-mesothelioma-06-26-2
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https://te.legra.ph/WHAT-IS-MALIGNANT-EPITHELIOID-MESOTHELIOMA-06-26-3
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https://telegra.ph/stage-mesothelioma-cancer-06-26-2
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https://telegra.ph/mESOthELiOMA-frOM-AsBEsTos-ExPosuRE-06-26-7
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https://tgraph.io/mesotheLIOMA-SYMPtOms-anD-CAuSeS-06-26-5
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https://te.legra.ph/Desmoplastic-Mesothelioma-Pathology-Outlines-06-26-3
https://tgraph.io/mesothelioma-related-lung-cancer-06-26-3
https://telegra.ph/how-many-mesothelioma-cases-per-year-06-26-2
https://te.legra.ph/caN-yOu-treaT-MeSOThELiOmA-06-26-5
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https://tgraph.io/HOw-DO-yOu-Get-mesOtHeLIOma-cANCER-06-26-4
https://telegra.ph/HOW-MANY-CASES-OF-MESOTHELIOMA-PER-YEAR-06-26-2
https://telegra.ph/mesothelioma-peritoneal-symptoms-06-26-4
https://telegra.ph/Stage-Iv-Malignant-Mesothelioma-06-26-4
https://te.legra.ph/iS-mESOTHELIOMA-sMALL-cELL-lUNG-cANCER-06-26-2
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https://tgraph.io/malignant-mesothelioma-biphasic-type-06-26-4
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https://telegra.ph/epithelial-mesothelioma-prognosis-06-26-2
https://telegra.ph/symptoms-of-abdominal-mesothelioma-06-26-2
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